Thursday, September 25, 2008

Don't drink juice and take meds!!

A new study has discovered that drinking juice around the time you take a medication might dramatically decrease its effectiveness:
Drinking fruit juice dramatically reduces the effectiveness of drugs used to treat cancer, heart conditions and high blood pressure, scientists say.

Research has shown that orange, apple and grapefruit juice can also wipe out the benefits of some antibiotics and hay-fever pills.

It is thought the drinks stop drugs from entering the bloodstream and getting to work in the body - possibly rendering them useless.

The potential effects are so serious, researchers warned, that if in doubt, patients should swap fruit juices for water when on medication.
[...]
The study showed juices do not need to be taken at the same time as drugs to have a dangerous effect.

Those drunk up to two hours before can reduce drug absorption.

But patients need not stop drinking juice altogether.

Professor Bailey said: 'Juice taken four hours prior to drug intake did not have an effect. Thus, it should be possible still to take grapefruit, orange and apple juices while on affected medications provided there is a sufficient time interval.

'I would recommend taking drugs with water on an empty stomach to get the most consistent effect.'
[...]
Professor Bailey made the link after asking volunteers to take the hay fever drug fexofenadine at the same time as either a glass of water or grapefruit juice.

Taking it with juice cut its absorption into the bloodstream by half.

Experiments showed naringin, the chemical which makes grapefruit taste bitter, blocked the drug from moving from the small intestine into the bloodstream.

The researchers have pinpointed a naringin-like compound in orange juice and are looking for a similar one in apples.

A different mechanism is at play with the drugs whose levels are boosted by grapefruit juice.

There, juice deactivates a liver enzyme that breaks down drugs, making normal doses potential overdoses.

The study is not the first to highlight the dangers behind supposedly healthy juices.

Last month, research from Harvard Medical School in the U.S., showed that one glass of orange juice a day can increase the risk of a form of diabetes linked to poor diet and obesity.

But eating whole pieces of fruit cuts the likelihood of developing the disease. It is thought the lack of fibre in juices may cause spikes in blood sugar levels.
Wow! That's incredible. I often take medication with juice. Just this week, when I had the flu, I drank a lot of juice to keep hydrated. I guess I invalidated part of the medicines I took.

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